2012 PhD Student Position in Molecular Cytology at University of Amsterdam, Netherlands

Sponsored Links

University of Amsterdam offers PhD Student Position in Molecular Cytology at Faculty of Science – Swammerdam Institute for Life Sciences, Netherlands 2012

Study Subject(s):Molecular Cytology
Course Level:PhD
Scholarship Provider: University of Amsterdam
Scholarship can be taken at: Netherlands

Eligibility:
-Master’s degree in Molecular Biology, Celbiology or Biochemistry (or equivalent)
-Experience with microscopical techniques
-Experience with data analysis techniques
-Ability to work in a team and independently
-Highly motivated to pursue a career in science Background/expertise in (epigenetic) gene regulation

Scholarship Open for International Students: No

Scholarship Description: The development of a multicellular organism involves constant changes in gene activity in a stage- and tissue-dependent manner. Instrumental to this multicellular development is the ability of the nucleus to modify its program by switching on or off whole sets of genes and changing its protein and RNA composition. Understanding which biological mechanisms underlie nuclear re-programming is a major challenge and one of the key objectives of our group. We study the organization of chromosomes and the spatial position of chromosomal loci in interphase nuclei of A. thaliana in relation to their activity. One of our goals is to map physical interactions in plants between chromosomal regions, such as regulatory sequences and their cognate genes. The aim of this project is to identify 3D positions of genomic loci and proteins in nuclei from leaf and apex tissues of A. thaliana and maize. The PhD student will apply a combination of immunolabeling and FISH techniques to analyse the location of proteins and target sequences involved in flowering. Using confocal microscopy, he/she will measure the frequency of co-localization of sequences of interest and the spatial position relative to other loci, proteins and nuclear reference points such as chromocenter, nuclear envelop or nucleolus. A whole-mount FISH approach will be used to verify and quantify chromosomal interactions identified by EpiTRAITS collaborators in single cells. The generated data will be used to construct a predictive model for the functional 3D-organization of chromosomes. To achieve our goals we will collaborate with several different partners within the EpiTRAITS consortium. This project will be supervised by Dr Paul Fransz.

How to Apply: By Post

Scholarship Application Deadline: 1 October 2012.

Further Scholarship Information and Application

Scholarship Tags: , , , , , , , , , , ,

Find it useful? Share Online - If you can, help others.
Sponsored Links
Warning: There is no need to provide bank account details or payment to any person or organization when applying for a scholarship or positions.Never give your bank account information, credit card or social security number to a prospective employer. Do not accept any offers to cash checks or wire money. If these details are requested for any job you see on scholarship-positions.com, please report the job to our quality team.

Important: Scholarship-Positions.com is not responsible for the content of any external websites linked to or referenced on this site.

Browse Scholarships

Search International Scholarships and Financial Aid Positions