Graduate Studies in Biomedicine, Microscopy and Biophysics Germany

January 28, 2008

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Graduate Studies in Biomedicine, Microscopy and Biophysics

The Rudolf Virchow Center is one of the first DFG-funded „Centers of Excellence“ and is devoted to research on target proteins such as receptors and signaling proteins. The graduate students are a part of the Graduate School of Life Sciences at the University of Würzburg, which is funded through the „Excellence Inititative of the Federal and State Government“. The molecular microscopy group (AG Harms) is seeking highly motivated

Graduate Students
to perform research in the following subject areas:
•       Imaging and molecular interactions of developmental processes in living animal models
•       Imaging and tracking of cytokine and G-Protein coupled receptor interactions and their signalling pathways in model and primary cell lines
•       Functional studies of ion channels and transporters with electrophysiology, biochemi-cal and biophysical techniques

Qualified applicants will either have completed a diploma or masters degree with high marks in Biology, Chemistry, Physics or in a nearly related field. Prior laboratory experience prefer-rably in molecular biology, biochemistry, and/or biophysics is essential. Applicants should have a desire to participate in collaborative, interdisciplinary work.
The research group is committed to the application and assembly of biosensors and their im-plementation in important transgenic model organisms, optical microscopes, and biophysical and biochemical techniques aimed at the better understanding and cure of cancer and cardi-ovascular diseases. The group is working higly collaborative and interdisciplinary within the University of Würzburg and also internationally.

Participitation at the Graduate School of Life Sciences will offer special courses to comple-ment an individual’s personal needs to complete interdisciplinary research.

The salary will be paid according to the regulations of the State of Bavaria (TV-L). Interested applicants should submit their applications (CV, diploma, courses, and examinations) and references within four weeks from publication date. Female applicants are particularly encou-raged to apply. Handicapped individuals with the same qualifications will be given preferren-tial consideration.

Prof. Dr. Gregory Harms
Rudolf Virchow Center
Versbacher Str. 9
D-97078 Würzburg, Germany
Phone +49-931-201 48717
Fax +49-931-201 48702.
E-mail: gregory.harms@virchow.uni-wuerzburg.de
www.rudolf-virchow-zentrum.de

Methoden:
Molecular Biology, PCR, Cloning, Optical Microscopy, Western Blotting, see description above

Anfangsdatum: 27. Januar 2008

geschätzte Dauer: 3 years

Bezahlung: TV-L Bavaria

Veröffentlichungen:
1. Gromova, K., Friedrich, M., Noskov, A., Harms, G.S. (2007) Visualizing SMAD1/4 signaling Response to Bone Morphogenetic Protein-4 activation by FRET biosensors. BBA Mol. Cell Res, 1773, 1759-1773.

2. Vilardaga, J.P., Steinmeyer, R., Harms, G.S., Lohse, M.J. (2005) Molecular basis of inverse agonism in a G protein-coupled receptor. Nat Chem Biol, 1, 25-28.

3. Harms, G. S., G. Orr, et al. (2003). Combined patch-clamp and single-molecule imaging Microscopy study of single-molecule ion channel dynamics. Biophys J, 85, 1826-1838.

4. Harms, G. S., L. Cognet, et al. (2001) Single-Molecule Imaging of L-Type Ca2+ Channels in Live Cells. Biophys J, 81, 2639-2646.

Homepage: http://www.virchow-zentrum.uni-wuerzburg.de/forschung/index.php?rubric=harms

Students from diverse fields are encouraged to apply.

Scholarship Tags: Biomedicine, germany, Graduate Studies, Microscopy Biophysics