PhD fellow in Fetal Programming of Early Onset of Metabolic Disorders, Denmark

July 24, 2010
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PhD Scholarship, Faculty of Life Sciences, University of Copenhagen, Fetal metabolic programming

Job Description: Research conducted during the past decades has shown that periods of undernutrition during fetal development may induce a phenomenon termed fetal metabolic programming. This is associated with increased risk later in life of developing metabolic disturbances like type 2 diabetes and obesity. Evidence is now accumulating to suggest that a fetal nutritional insult also in the form of overnutrition is a significant risk factor predisposing for postnatal development of metabolic disturbances and early onset obesity. Childhood obesity is an increasing problem and it is estimated that by 2010 more than 40% of European children will be overweight or obese.

With reference to the project manager and within the framework of a newly founded Centre for Fetal Programming, the work of the Ph.D. fellow will consist mainly of duties related to experimental studies with sheep as models for humans. The aim is to study the age related and tissue specific developments of metabolic disorders later in life as a consequence of fetal programming in response to gestational overnutrition as compared to undernutrition. It is furthermore the aim to study how the diet in early postnatal life may influence the phenotypic expression of metabolic disorders later in life in an individual who has undergone adverse programming during fetal life.
The appointee should have qualifications within the following areas:
* (Animal) physiology and nutrition
* In vivo pharmacology and experimental animals
* Knowledge of or interest in methodologies related to molecular biology genomics, epigenomics, miRNA, histology, immunohistochemistry)
* Biostatistics

Qualification requirements
In connection with the appointment to the post special importance will be attached to the applicant having the professional and personal qualifications stated below:

* Passed Master´s degree in animal science, (veterinary) medicine or similar relevant biological background
* Good command of English

The Ph.D. fellow is also required to have research potential, to be enterprising and to possess good interpersonal skills.

Terms of employment
The post will be filled according to the Agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. The post is covered by the Protocol on Job Structure.

The position as Ph.D. fellow requires the applicant to be approved for admission to the Ph.D. programme at LIFE when accepted for the post.

Questions
For further information about the post, please contact project manager Assoc. Prof. Mette Olaf Nielsen on tel. (+45) 353 33065, mon@life.ku.dk.

General questions regarding Ph.D. programmes should be directed to Course Administration c/o special advisor Michael Cleve Hansen, tel. + 45 3533 2056 or head clerk Lillian Zeuthen Bjørnseth on tel. +45 3533 2172. Further information on Ph.D. programmes is available at www.life.ku.dk/English >Education > PhD Education > Regulations.

Application
The application should be submitted in 2 (sorted) copies; therefore it is not possible to receive the application by e-mail. The application must include a reply e-mail address. Each application must include the following appendices marked with the stated appendix numbers:

Appendix 1: curriculum vitae with documentation of education.
Appendix 2: material required for expert assessment.

In addition to the material the applicant wishes to be included in the assessment, the Assessment Committee may include further material in their assessment of the applicant. In such circumstances, it is the responsibility of the applicant, on request, to send the material to the Committee.

Following processing of the application, any application material sent will be destroyed.

Receipt of the application will not be acknowledged, but the applicant will be kept continuously informed of the progress of the application.

The applicant will be assessed according to the Ministry of Science Technology and Innovation Executive Order no 284 of 25. April 2008.

The application, marked 625/05368-267 should be sent to The Faculty of Life Sciences, Department of Basic Animal and Veterinary Sciences, Grønnegårdsvej 7, DK-1870 Frederiksberg C, where it must be received no later than 15 October 2010 at 12.00 noon. Applications received after the closing date for applications will not be considered.
Deadline: 15-10-2010

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