PhD Position in Max Planck Institute for Plant Breeding Research,Germany

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May 17, 2010

Job Description :Due to their sessile life-style, plants are directly exposed to abiotic stresses, including those causing DNA damage. To survive unfavourable conditions, plants have evolved a complex DNA damage surveillance and repair machinery to control and maintain genome integrity. Loss of this control frequently leads to chromosomal aberrations, reduced fitness and, in extreme cases, lethality. Sources of DNA damage (e.g. free radicals, UV light) are unequally distributed in nature. Thus, wild populations  exposed to enhanced rates of DNA damage have very likely evolved compensatory mechanisms leading to more effective DNA protection and/or repair. The proposed PhD project will focus on discovery and characterization of variability in DNA damage repair among natural populations of the model plant Arabidopsis thaliana. To this end, genetic, molecular, bioinformatic and biochemical tools will be employed. The results will allow an understanding of the mechanisms of DNA repair and genomic adaptations to local environmental conditions.

Requirements:

The applicant should be highly motivated and possess an MSc or equivalent in Life Sciences. Previous experience in genetic mapping, molecular biology or DNA repair is an advantage.

Application details :

Please submit your application including a CV and contact details for two referees till August 1st, 2010, to: pecinka@mpipz.mpg.de.

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