PhD Position Leiden Institute of Physics Leiden University The Netherlands

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March 5, 2008

PHD POSITION
Dynamics of proteins by electron paramagnetic resonance (f/m)
vacancy number: 8-053

Research
Proteins are unique machines that convert molecules or generate force. Understanding how they work requires to determine their structure and to detect their motion during function. By Electron Paramagnetic Resonance (EPR) structure is accessible via the dipole-dipole interaction of electron and/or nuclear spins from tenths of nanometers to several nanometers. Motion can be measured from nano-seconds to milliseconds. To develop and apply suitable methods to investigate the molecular mechanism of proteins is the aim of the project.

Job description
Developing and improving EPR methods to determine distances and dynamics of biological samples. Application of these techniques to understand protein function on a molecular level. The project is an interdisciplinary biophysics project, with subjects ranging from instrumental development in EPR to the biochemical aspects of protein manipulation.

Location
The project is carried out in the MoNOS (Molecular Nano-Optics and Spins) group at the Leiden Institute of Physics, Leiden University

Requirements
Candidates should have a

* strong interest in biophysics and be motivated to work on an interdisciplinary project.
* background in biophysics, molecular spectroscopy and measurement techniques (Experience in EPR is welcome, but is not required per se.)
* Hands-on experience in spectroscopy, physical chemistry or experimental physics is absolutely required.

In the context of the promotion of Indian-Dutch co-operation, we explicitly invite Indian applicants to respond

Conditions of Employment
When fulfilling a PhD position at the “Stichting voor Fundamenteel Onderzoek der Materie” (FOM foundation), you will get the status of junior scientist.
You will have an employee status and can participate in all the employee benefits FOM offers. You will get a contract for 4 years. Your salary will be up to a maximum of 2,457 euro gross per month.
You are supposed to have a thesis finished at the end of your four year term with FOM. For details, see also the links under http://www.fom.nl/live/vacatures/vacature.pag?objectnumber=73001

Contact
Dr. Martina Huber
Huygens Laboratory
MoNOS Group
Leiden University
P.O. Box 9504
2300 RA Leiden
The Netherlands
tel: +31 (071) 527 55 60
Website
www.monos.leidenuniv.nl
For details of the Indian-Dutch collaboration program: www.dutchsciencecareers.in

Applications
You can send your application by email mhuber@molphys.leidenuniv.nl

or to the following address:

Martina Huber
Huygens Laboratory
MoNOS Group
Leiden University
P.O. Box 9504
2300 RA Leiden
The Netherlands

Closing date: March 23rd, 2008

Scholarship Tags: Institute, Leiden, PhD, Physics, Position, The Netherlands, University