PhD position – Molecular Structure of Apolipoproteins – 3 years (Graz, Österreich)
Project summary :
The aim of this project is to explore the three dimensional domain structure of lipid-free apolipoprotein B100 (apo-B100), which is the only protein moiety of the primary human cholesterol carrier low density lipoprotein (LDL), and of defined fragments thereof, as well as of avian apo-VLDL-II, which is the most effective endogeneous inhibitor of the important enzyme lipoprotein lipase known.
Detailed information on www.fwf.ac.at project-database /project number P20455.
Starting date : March 2008
Salary :According to the salary schemes of the Austrian FWF
Job description
We are looking for a highly motivated student to meet the challenge to solve the structure of human apolipoproteins and to tackle a demanding but fascinating topic. Focus of work is on protein purification, biophysical characterisation, crystallisation, low resolution structure determination by small angle X-ray scattering and X-ray protein crystallography.
Requirements
The candidate must hold a MSc degree and should have a basic background in biochemistry, laboratory experience, computer skills and be conversant with concepts of lipoproteins and/or membranes.
Prassl Ruth
ruth.prassl@oeaw.ac.at
Institut für Biophysik und Nanosystemforschung, Österreichische Akademie der Wissenschaften
Graz, Österreich
Scholarship Tags: Graz, Molecular Structure of Apolipoproteins, PhD position, Österreich
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