PhD Position, University of Zurich, Switzerland
PhD or MD/PhD student for 3 years at the Institute of Physiology and Division of Nephrology at the University of Zurich, Switzerland. Start: 01 October 2008 or later.
Project:
Glomerular proteinuria, normally prevented by the permselective glomerular filter in the kidney, is an indicator for the development of end-stage renal failure and cardiovascular complications. The aim of the project is to decipher mechanisms leading to the loss of protein through the renal glomerulus.
We will analyze a unique data set of already established glomerular gene expression profiles from patients with the main acquired proteinuric glomerulopathies. A recently generated library of genes predominantly expressed in the glomerulus will be used to identify molecular mechanisms particularly relevant in this renal compartment.
Using these data sets regulatory pathways linked to specific or all proteinuric diseases will be analyzed using bioinformatic characterization. This will lead to confirmatory studies in vitro on cell lines of all relevant glomerular cell types. Pathway interference in these cells is planned using siRNA as well as transient or stable transfection. Computer-predicted promoter characteristics will be evaluated by promoter-reporter construct analysis and could be confirmed by DNase footprinting and chromatin immune precipitation. Further evaluation by immunohistology can be performed on an archival biobank.
In parallel, marker transcripts for clinical outcome and response to therapy will be identified by correlation of gene expression profiles with already available clinical follow-up data.
Profile:
We are looking for a friendly and highly motivated new member in our team. A degree in Biology, Biochemistry or Medicine would be ideal.
The work would be partially computer-assisted (array analysis, pathway identification, promoter analysis) and wet bench (glomerular cell studies, siRNA, transfection, if interested promoter interference and/or immunohistology). No animal studies planned for this period of the study.
Clemens D. Cohen
clemens.cohen[a]access.uzh.ch
Universtity of Zurich
Zurich, Switzerland
Ansprechpartner: Clemens D. Cohen; http://www.physiol.uzh.ch/research/MechanismsOfAcquiredNephropathies.html
Scholarship Tags: Biology, PhD position, Switzerland, University of Zurich
Scholarship Search
Important: Scholarship-Positions.com is not responsible for the content of any external websites linked to or referenced on this site.
Browse Scholarships
- Africa Scholarships
- Australia Scholarships
- Austria Scholarships
- Belgium Scholarships
- Canada Scholarships
- China Scholarships
- Denmark Scholarships
- France Scholarships
Recent USA Scholarships
Philip and Euline Seecharan Scholarship at Florida International University, USA 2012 2012 Benjamin A. Gilman International Scholarship, USA Laurey T. Stryker Scholarship at University of South Florida, USA 2012 USM School of Education and Human Development (SEHD) Graduate Scholarship, USA 2012-2013 Entrepreneurship Scholarship at Elizabethtown College, USA 2012Recent UK Scholarships
2012 IBERS International Masters Scholarships, UK University of Kent Dental Development Scholarship for Undergraduate Students, UK 2012 2012 Reham al-Farra International Scholarship in Journalism at Bournemouth University, UK Social Science Master’s Scholarship for International Scholarships at the University of Southampton, UK 2012 University of Warwick International Office Masters Scholarships 2012, UKRecent Germany Scholarships
PhD in Life Sciences at The International Giessen Graduate School for the Life Sciences, Germany Germany Postgraduate Training Program – 2012 Cycle (PhD studies in Germany) HBIGS 12 MSc/ PhD Fellowships at Heidelberg University, Heidelberg, Germany PhD Studentship in Polymer Sciences at German Institute for Polymers, Germany Postdoctoral/ PhD Student Postions in Genome Biology at GRK1721, 2012 GermanyRecent India Scholarships
FedBank Hormis Memorial Foundation Scholarships 2012, India Commonwealth Scholarship Plan for Indian Students, New Zealand Ms. Agatha Harrison Memorial Fellowship for the Year 2012-13, UK 2012 The Tara Nirula International Students House (ISH) for Indian Students at University of the Arts London, UK Assistantship for Master’s Students at Indian Institute of Technology-Kharagpur, India 2012Women Scholarships
Call for Applications: Women Scientists Scheme (WOS-C) Training, India 2012 HHL Scholarship for Women in Business, Germany 2012 University Hall St Andrews Graduates’ Association (UHStAGA) Scholarship, UK 2012 International Fellowships Programme for Women in Japan WIA Foundation Annual 2012-2013 Scholarship for Women, USAAfrica Scholarships
2012 Disability Rights Scholarship Program at University of Pretoria, South Africa 2012 TBA Masters Scholarship for African Students, Africa The University of Pretoria Research Development Programme, 2012 South Africa EK BROWN Bursary 2012 in Veterinary Science, South Africa Hewlett Foundation/Institute of International Education Dissertation Fellowship, 2012Scholarship Blog
Useful Links
Search in Worldwide UniversitiesOxford Laboratory Technology
Search Courses in Indian Universities
IndiaJobs.co.in, India Jobs Employment, Recruitment, Careers, Interview
Teaching, Professor Jobs in India
GRE Prep and Free Courses