PhD Student Positions in Genomics University of Munich

July 23, 2008
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PhD Student Positions – Evolutionary/Functional Genomics

Two PhD student positions in Evolutionary and Functional Genomics are
available at the University of Munich. The students will join a
collaborative research group studying natural selection in structured
populations and be enrolled in the Munich Graduate School for
Evolution, Ecology and Sytematics (EESLMU). The specific projects are:

1) Selection on expression variation at the B4galnt2 gene in natural
populations of house mice (Dr. John Baines). Variation in the
tissue-specific expression pattern of B4galnt2, a glycosyltransferase,
is associated with a phenotype in mice that closely resembles a common
human bleeding disorder, von Willebrand disease. This project aims to
understand the evolutionary forces governing this variation and will
include a large-scale geographic survey of alleles conferring
alternative expression patterns and an analysis of metagenomic samples
from wild-caught mice.

2) Gene expression variation in natural populations of Drosophila (Dr.
John Parsch). This project will use microarray analysis to investigate
gene expression variation in Drosophila melanogaster, with particular
focus on adaptive regulatory changes between ecologically
differentiated populations. It will also include DNA sequence analysis
and transgenic experiments to study the evolution of gene regulatory
elements.

The University of Munich has a strong, interactive group in
evolutionary biology, including theoreticians and experimentalists
working on both plant and animal systems. We have an international
group and the everyday working language is English. The Department of
Biology is housed in the new, state-of-the-art BioCenter on the
University of Munich High-Tech campus. More information is available on
the web at:

http://evol.bio.lmu.de/EvoGen.html

PhD students will receive a salary according to the German pay scale
(E13/2 TV-L). Applicants should have a master’s degree or equivalent in
biology or a related field. In addition, laboratory experience in
molecular biology and/or genetics is desired. Interested candidates
should send a CV, statement of interest, and contact information of two
potential referees as a single PDF file to:

baines@bio.lmu.de

Applications will be reviewed beginning August 15, 2008. The positions
are expected to start on November 1, 2008.

The University of Munich is an Equal Opportunity/Affirmative Action
Employer and has an affirmative action policy for the disabled.

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