PhD Studentship-Defining the Opposing Roles of HLXB9 in Myeloid and Lymphoid Leukaemia, Newcastle University, UK

Share



Sponsored Links
Career Blog
July 17, 2010

Job Description:

HLXB9 is a homeobox containing transcription factor that has previously been shown to be expressed at high levels in CD34+ haematopoietic cells, suggestive of a role in haematopoietic differentiation. Previous studies have suggested that HLXB9 can function as an oncogene in infant acute myeloid leukaemia (AML) but as a tumour suppressor in solid tumours. Furthermore, we have recently demonstrated that it is frequently epigenetically inactivated in acute lymphoid leukaemia (ALL), suggesting a tumour suppressor role in lymphoid leukaemia. In this project we will investigate the function role of HLXB9 in both ALL and AML cells. Both the WT gene and HLXB9 fused to ETV6 will be assessed for a function role in control of cell proliferation, survival and differentiation. In addition we will further investigate the frequency of the HLXB9-ETV6 fusion in infant leukaemia and identify other cytogenetic abnormalities leading to disruption of these genes. Through these studies we will determine the extent and importance of disruption of normal HLXB9 expression in both AML and ALL.

Value of the Award and Eligibility
The award will cover full fees for UK and EU students and will provide a competitive stipend (£13,650 in the first year). International students may apply but the fees will only be paid at the UK/EU level

Person Specification
Candidates must have a BSc in an appropriate scientific specialty at either a first-class or upper-second-class Honours level or equivalent. Previous research experience or a Master’s degree would be advantageous

How to Apply
You must complete the University’s postgraduate application form. Select “Doctor of Philosophy (Medical Sciences) – Ageing and Health” as the programme of study. Only mandatory fields need to be completed (no personal statement required) but you must attach a copy of your CV and a covering letter, quoting the title of the studentship and reference number IA044.

Closing date for applications: Friday 23rd July 2010

For further details:

Scholarship Tags: , , , , , ,

Sponsored Links

Scholarship Submitted by team | in Category PhD Scholarships, UK Scholarships

Scholarship Comments and Discussion

Sponsored Links

Scholarship Search

Warning: There is no need to provide bank account details or payment to any person or organization when applying for a scholarship or positions.Never give your bank account information, credit card or social security number to a prospective employer. Do not accept any offers to cash checks or wire money. If these details are requested for any job you see on scholarship-positions.com, please report the job to our quality team.

Important: Scholarship-Positions.com is not responsible for the content of any external websites linked to or referenced on this site.

Browse Scholarships

Search International Scholarships and Financial Aid Positions

Receive Scholarship Newsletters

Over 1,000,000 Students Searching Scholarships.

Recent USA Scholarships

Vanderbilt Postdoctoral Research at Vanderbilt University School of Medicine, 2012/13 USA 2012-2013 Fulbright NEXUS Regional Scholar Program, USA 2012 R G Menzies Scholarships for Australian Citizens, USA TLMI 4 Year College Degree Scholarship Program, USA 2012 2012-13 TLMI 2 Year College Degree Scholarship Program, USA

Recent UK Scholarships

RIBA Aedas Stephen Williams Scholarship in Architecture, 2012/13 RIBA Norman Foster Travelling Scholarship in Architecture, 2012 2012 Research Position in Pure Mathematics at University of Bristol, UK Postdoctoral Research Position in Synthesis and Analysis of Peptide-Based Porous Materials, UK Postdoctoral Research Position in Structural Engineering at University of Liverpool, UK 2012

Recent Germany Scholarships

PhD Studentship in Polymer Sciences at German Institute for Polymers, Germany Postdoctoral/ PhD Student Postions in Genome Biology at GRK1721, 2012 Germany Bucerius PhD Scholarship in Migration Studies, 2012 Germany PhD Position in Theoretical Physics at Humboldt University Berlin, Germany Doctoral – Postdoctoral Program in Mathematics Education in Germany 2012

Recent India Scholarships

2012 Summer Research Fellowships in Engineering at IIT Delhi, India The Ravi Sankaran Fellowship Program for Indian Students, 2012 Trinity College Dublin Scholarships for Postgraduate Students, Ireland 2012 2012 Henley Business School Scholarship India at University of Reading, UK POCE/POBE Scholarship Programme at Jawaharlal Nehru Centre for Advanced Scientific Research- Bangalore, India

Women Scholarships

Call for Applications: Women Scientists Scheme (WOS-C) Training, India 2012 HHL Scholarship for Women in Business, Germany 2012 University Hall St Andrews Graduates’ Association (UHStAGA) Scholarship, UK 2012 International Fellowships Programme for Women in Japan WIA Foundation Annual 2012-2013 Scholarship for Women, USA

Africa Scholarships

Postdoctoral Research Fellowship in Geology for Australian Citizens in Tanzania, 2012 2nd Joint Call Research Proposal in Population, Reproductive Health and Economic Development, 2012 The 2012 TechWomen Professional Mentorship and Exchange Program, USA Internship Programme at African Development Bank, 2012 Africa MPhil / PhD Research Internships at PLASS Institute for Poverty, Land and Agrarian Studies, South Africa

Scholarship Blog

Useful Links

Search in Worldwide Universities
Oxford Laboratory Technology
Search Courses in Indian Universities
IndiaJobs.co.in, India Jobs Employment, Recruitment, Careers, Interview
Teaching, Professor Jobs in India
GRE Prep and Free Courses