PhD Thesis Position at University of Heidelberg Germany

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July 12, 2008

Position available for a PhD thesis,at the II. Medical Clinic, Gastroenterology and Hepatology, Medical Faculty at Mannheim, University of Heidelberg The Section of Molecular Alcohol Research in Gastroenterology is performing basic and clinical research in the fields of chronic liver disease.
We offer a vacant position for a PhD thesis. The position will be integrated into an active research environment.

We are looking for an enthusiastic student of biology, chemistry or biochemistry with basic experience in experimental techniques of molecular biology, cell culture, cloning and microscopy.
The project is integrated in the ENDOSYS network of HepatoSys and focuses on the development of novel tools for live cell imaging in primary hepatocytes to monitor TGF-ƒÒ mediated signal transduction. Identification of key regulatory events in signal transduction pathways has been done so far by the usage of biochemical compounds blocking protein-protein interactions, by fluorescence based studies or siRNA knock-down, resulting in unphysiological conditions in the cell.
Aim of the proposed project is to develop intracellular antibodies with high specificity, constructed either to inhibit protein-protein interactions or conjugated with fluorophores, enabling visualization of dynamic processes with high resolution microscopy.

For more information please contact Dr. Anastasia Bachmann 0621/383-5595. Please send your application by email or conventional mail to:

Dr. Anastasia Bachmann
Molecular Alcohol Research in Gastroenterology Dept. of Medicine II Medical Faculty Mannheim University of Heidelberg Theodor-Kutzer-Ufer 1-3
68167 Mannheim

E-mail: Anastasia.Bachmann@medma.uni-heidelberg.de

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