Postdoctoral Position in NIH Multiscale Modeling of the Human Knee, Netherlands

August 4, 2010

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Postdoctoral Position,NIH Multiscale Modeling of the Human Knee,Eindhoven University of Technology,Netherlands

Job Description: The Department of Biomedical Engineering is a joint department of the Eindhoven University of Technology and the University of Maastricht interfacing and integrating engineering and biomedical sciences from the two universities. The department is organized into 4 divisions: 1) molecular bioengineering, 2) biomechanics and tissue engineering, 3) biomedical imaging and informatics, and 4) biosignals and regulation.

We are looking for a Post Doc in the division of Biomechanics and Tissue Engineering for an international NIH-funded project, in which researchers from TU/e are working together with colleagues from Lerner Research Institute in Cleveland, the University of Utah in Salt Lake City, and Duke University in Durham.

Project description: The goal of the consortium is to understand how mechanical loading, applied at the level of a whole knee joint, can be translated into mechanical effects in cartilage, ligaments and menisci, at multiple scales, down to the level of a single cell. To predict cellular deformations from joint level mechanical loading, requires a multi-scale finite element model. Such a model is being developed in this project, and will be used for studying physiological as well as pathological responses. Part of the project is to obtain experimental data at multi-scales, which can be used for model validation.

The task of the TU/e in this project is to develop micro-structural models for cells and pericellular and extracellular matrix that describe the deformation and failure behavior of the tissue. TU/e also is responsible for performing experiments for data collection and validation of the micro-structural models. This includes monitoring abnormal deformations at the micro-level, and to establish critical levels of magnitude, duration and/or frequency above which these can lead to cell damage and disruption of homeostasis of the extracellular matrix.

Requirements:

We are seeking a candidate who is well versed with computational analysis and knowledgeable of biological processes. The candidate should be recently graduated from a PhD – program in biomedical engineering, mechanical engineering, (bio)physics or a related field, with,

* Knowledge and experience in biomedical science and technology,
* Strong affinity for multidisciplinary research and engineering science,
* Experience with finite element modeling and ex vivo biomechanical testing,
* Capacity to write and communicate fluently in English.

Appointment and Salary:

We offer

* a challenging job at a dynamic and ambitious university in an international consortium with top institutes and universities from the United States
* an appointment for two years;

* gross monthly salaries in accordance with the Collective Labor Agreement of the Dutch Universities (CAO NU).

Application Deadline 30-09-2010

For further Fellowship Information

Scholarship Tags: Fellowship, Human, Knee, modeling, Netherlands