Postdoctoral Scholars in Drug Discovery Melatonin Receptors as Targets for Antidepressant Action
A postdoctoral research position supported by NIH funding is available immediately for a Ph.D. or MD/Ph.D. to study the neuropharmacology of MT12 melatonin receptor ligands as potential antidepressants. Projects include the use of mouse models with genetic deletion of the MT1 and/or MT2 and/or MT melatonin receptors and/or clock genes to understand the mechanism(s) of antidepressant actions of melatonin receptor ligands in molecular signaling and neurogenesis, and in their ability to show antidepressant effects in rodent models of depression.
Candidates must have a strong research background and practical experience with mouse behavior models, and the molecular neuropharmacology of G-protein coupled receptors and signaling. Candidates should be willing to use integrated neuropharmacology in vitro and in vivo approaches to assess the antidepressant efficacy of melatonin receptor ligands. Knowledge of the molecular mechanisms of clock gene expression and circadian behaviors is desirable as well. This position represents a unique opportunity for career development, for learning drug discovery approaches, and for having interactions with investigators within the multidisciplinary scientific community at Northwestern University.
Applications should include a cover letter summarizing career experiences and specific qualifications in the field of circadian rhythm neurobiology, a CV, and full contact information for at least 3 references. Submit applications directly Dr. Margarita L. Dubocovich [mduboatnorthwestern.edu; (312) 503-8005]. Deadline for receipt of completed applications is February 28, 2008. AA/EOE. We encourage applications from women and members of underrepresented groups.
Contact Dr. Margarita L. Dubocovich
E-mail: mduboatnorthwestern.edu
Phone: (312) 503-8005
Scholarship Tags: Action, Antidepressant, Drug Discovery, Melatonin Receptors, Postdoctoral Scholars, Targets
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