Quantitative mass spectrometry of oligomeric biomolecules – International Graduate School of Metrology
June 1, 2009Quantitative mass spectrometry of oligomeric biomolecules
Description : Analytes often form a group of homologues, regio and/or stereoisomers. Determination of group parameters does not take into account that biological activities – e.g. toxicity, mutagenic activity, antioxidant activity – are strongly related to the individual constitution and spatial orientation of a molecule and can thus differ significantly from related compounds. Mass spectrometry is a powerful tool to gain structural information on tiny amounts of complex mixtures, but cannot simply be used for quantification. Discrimination in mass spectrometry depends on sample preparation, ionisation conditions, ion transfer into the mass analyzer and type of analyzer. By means of appropriate labelling strategies, structural differences influencing ionisation yield can be overcome. Quantitative analysis of complex mixtures of, for example, oligosaccharides and polyphenols will be possible with appropriate instrumentation. Composition behind isobaric signals will be evaluated by tandem mass spectrometry. Diastereoisomers can be differentiated by their metal-coordinating properties, e.g. of diols or other chelating structural elements. Prof. Dr. Petra Mischnick You are required to hold an excellent university degree (master’s or equivalent degree) in physics, chemistry, electrical or mechanical engineering, mathematics, information technology or related fields. The entire program is run in English, so fluency in both written and spoken English is required. Skills in German are welcome. You may be a member of and receive a scholarship from the IGSM for up to 3 years. In your first semester, you will be accepted on a probationary basis. Please note that application is only possible online at www.igsm.tu-bs.de.
Homepage : www.igsm.tu-bs.de
Category : Engineering, Metrology
Contact address : www.igsm.tu-bs.de
Keywords :
Name : International Graduate School of Metrology
Tags: biomolecules, Engineering, Graduate, International, Mass, metrology, oligomeric, Quantitative, School, spectrometry
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I am a MSc industrial biotech student,8.22CGPA mark,2009 pass out student,can any lifescience phd is possible for me give details.
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P.O.BOX :1252/1000
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Ethiopia Email: yeshiwork.assefa@gmail.com
Dear : All
How are you ?
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I look forward to hearing from you soon
if possible would you guide me the way ?
My address is
Sisay Gobessa
Haramaya university
P.O.box 282 Haramaya , Ethiopia
Email: albert.instein2009@gmail.com
Dear Sir (Universities)
I acquired a BSc degree in Agriculture (Plant Sciences) from the then Alemaya University of Agriculture (recently Haromaya University) in 1990, Ethiopia.
After graduation, I was employed & working in different governmental organizations in the field of agriculture for the last 18 years with the academic knowledge I obtained from the University. However, I believe that involving in different up to date research keen challenges & specializing in subject matter (Further studies in Master & PhD Program) is important for my career. I am keen inserted to up- grade my knowledge and qualification with Research & Msc (Master) degree
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Thank you
Atenafu Demissie
Ethiopia
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