Vacant PhD position Institute for Pharmacy and Molecular Biotechnology IPMB, University of Heidelberg, Germany

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March 31, 2008

Applications are invited for a vacant PhD position (TVL13/2) to join a dynamic research group (Functional Genomics and Molecular Neurogenetics, headed by Prof. Ulrike Müller) at the Institute for Pharmacy and Molecular Biotechnology IPMB, University of Heidelberg.

We are is interested in the physiological and pathological function of proteins involved  in Alzheimer´s disease, in particular proteins of the β-amyloid precursor protein APP gene family (e.g. Herms et al., The EMBO J. 23, 4106;  Hebert et al., EMBO reports 7, 739; Ring et al. J. Neuroscience, 27, 7817). Although APP and its metabolism is central to the pathogenesis of Alzheimer´s disease the physiological and normal cell biological function of APP family proteins are poorly understood. Current projects focus on “The role of APP family proteins in the developing and adult nervous system” including the generation, function and maintenance of synapses. These studies will involve work with gene targeted mouse mutants and cells derived from them. Methods include molecular biology, biochemical, cell biological and histological techniques.

Applicants should be highly motivated  and hold a degree in Neurobiology, Biology, Medicine or Biochemistry. Experience in neurobiology, cell biology or biochemistry including the analysis of transgenic mice are an advantage.

If interested please send a short application including CV, statement
of research experience and interests, publications and names of two referees to u.mueller@urz.uni-hd.de or by mail to

Prof. Ulrike Müller
u.mueller@urz.uni-hd.de
Universität Heidelberg IPMB
Heidelberg

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